إعـــــــلان

**اميرة بدينها2** · 04-03-2011, 04:18 PM

رد: مراجعة فارماكولوجى للخريجين

جزاكم الله خيرا

بس أختى الكريمة هو يمكن صعب لل مش فى المجال الطبى لكن متهيألى الدكاترة والصيادلة بالنسبة ليهم مفهوم

وهحاول إن شاء الله إنه يكون فيه ترجمة بالعربى بس لو ممكن أخت تشارك معايا فى ذلك يكون أفضل

يعنى أنا أكتب الموضوع بالإنجليزى وهى تدخل بعدى تكتب الترجمة
وجزاكم الله خيرا

**نور_الاسلام** · 04-03-2011, 06:09 PM

رد: مراجعة فارماكولوجى للخريجين

بارك الله فيكي أختي وحفظك الله ورعاكي

**اميرة بدينها2** · 09-03-2011, 06:12 PM

رد: مراجعة فارماكولوجى للخريجين

question on antihypertension drugs
http://www.pharmacology2000.com/learning2.htm
An elderly male patient has essential hypertension, congestive heart failure, and type I insulin-dependent diabetes. His congestive failure developed secondary to coronary vascular disease associated with hyperlipidemia. What antihypertensive drug(s) may be most appropriate for this patient?
? chlorothiazide (Diuril)
? captopril (Capoten)
? propranolol (Inderal)
? metoprolol (Lopressor)
Total peripheral resistance (TPR) is a determining factor for mean arterial pressure, i.e. Mean arterial pressure (MAP) = cardiac output x total peripheral resistance (TPR). What are correct relationships between norepinephrine, minoxidil, and lisinopril and TPR?
? minoxidil (Loniten): TPR increases
? fosinopril (Monopril): TPR increases
? norepinephrine (Levophed): TPR increases
? phenoxybenzamine (Dibenzyline): TPR increases
Side effects of this antihypertensive agent includes tachycardia, angina, reversible lupus-like syndrome
? propranolol (Inderal)
? mecamylamine (Inversine)
? hydralazine (Apresoline)
? diazoxide (Hyperstat)
Mechanism of action:diltiazem (Cardiazem)
? phosphodiesterase inhibitor
? blockade of calcium channels
? alpha-1 receptor antagonists
? beta-1 receptor antagonist
Blocks both alpha and beta receptors:
? timolol (Blocadren)
? labetalol (Trandate, Normodyne)
? propranolol (Inderal)
? diazoxide (Hyperstat)
ACE inhibitor
? nifedipine (Procardia, Adalat)
? captopril (Capoten)
? timolol (Blocadren)
? methyldopa (Aldomet)
Drug intervention for acute management of aortic dissection in which the objective is to reduce shear forces generated by blood flow:
? hydralazine (Apresoline)
? nitroprusside sodium (Nipride)
? nitroprusside sodium (Nipride) + propranolol (Inderal)
? A & C
Antihypertensive drugs belonging to the same class:
? doxazosin (Cardura), prazosin (Minipress), metoprolol (Lopressor)
? nifedipine (Procardia, Adalat), verapamil (Isoptin, Calan), diltiazem (Cardiazem)
? clonidine (Catapres), guanabenz (Wytensin),terazosin (Hytrin)
? lisinopril (Prinvivil, Zestril), fosinopril (Monopril), guanadrel (Hylorel)
Tachycardia observed after minoxidil (Loniten) may be blocked by:
? mecamylamine (Inversine)
? propranolol (Inderal)
? both
? neither
Calcium channel blocker: vasodilation, less likely to have direct cardiac effects:
? nifedipine (Procardia, Adalat)
? diltiazem (Cardiazem)
A patient presents with a blood pressure of 160/110 mm Hg. The patient has a history of coronary vascular disease, resulting in angina, but has no evidence of congestive heart failure. The patient also has asthma and has been treated mainly using terbutaline (Brethine), by aerosol inhalation Propranolol (Inderal) was prescribed to manage essential hypertension. Was this action appropriate?
? Propranolol (Inderal) is appropriate because it will reduce heart rate and cardiac output. Negative inotropism will help reduce the incidence of angina. It is an effective antihypertensive agent
? Propranolol (Inderal) is inappropriate because it is only useful in mild hypertension; a better drug would be minoxidil or hydralazine because they are more effective in lowering blood pressure
? Propranolol (Inderal) is appropriate because it is an effective, low-cost antihypertensive. It will augment the effects of terbutaline, an additional benefit
? Propranolol (Inderal) is inappropriate because its use is contraindicated in a patient with asthma.
Hypertensive emergencies:
? diltiazem (Cardiazem)
? nitroprusside sodium (Nipride)
? reserpine
? phenylephrine (Neo-Synephrine)
Ganglionic blocker
? prazosin (Minipress)
? hydralazine (Apresoline)
? mecamylamine (Inversine)
? nicardipine (Cardene)
Minoxidil (Loniten) administration produces arteriolar vasodilation with little effect on capacitance vessels. Drug(s) acting similarly:
? nitroprusside sodium (Nipride)
? propranolol (Inderal)
? hydralazine (Apresoline)
? A & C
Vasoconstriction, aldosterone secretion, and renin release suppression occur upon activation of the renin-angiotensin-aldosterone system. How would captopril (Capoten) affect these responses?
? blocks all three
? blocks only vasoconstriction
? blocks all except vasoconstriction
? no effect
Mechanism of action: prazosin (Minipress)
? alpha-1 receptor blocker
? beta receptor blocker
? phosphodiesterase inhibitor
? calcium channel blocker
Antihypertensive: action based on inhibition of norepinephrine release from adrenergic nerve endings:
? propranolol (Inderal)
? guanadrel (Hylorel)
? mecamylamine (Inversine)
? phentolamine (Regitine)
Antihypertensive drug LEAST likely to elevate serum lipids:
? propranolol (Inderal)
? metoprolol (Lopressor)
? chlorothiazide (Diuril)
? diltiazem (Cardiazem)
i.v. route of administration; few side effects; effective in treating hypertensive crisis:
? nifedipine (Procardia, Adalat)
? nitroprusside sodium (Nipride)
? nicardipine (Cardene

**~باغية الجنان العلى~** · 10-01-2012, 11:06 PM

رد: مراجعة فارماكولوجى للخريجين

الروابط مش شغالة

يا ريت لو تعرفي تكملي الموضوع اخيتي
محتاااااااجااااه جداااا

**اميرة بدينها2** · 08-07-2012, 09:37 PM

مراجعة فارماكولوجى للخريجين

http://www.mediafire.com/view/?5l7dct8jle114c0

http://www.mediafire.com/view/?f5lgbktbc9mcr8v

http://www.mediafire.com/view/?f5lgbktbc9mcr8v

مقدمة فى علم الفارماكولوجى

**طريقي لربي** · 09-07-2012, 12:20 AM

رد: مراجعة فارماكولوجى للخريجين

ماشاء الله
راااااااائع جدااااا اختى اميرة بدينها 2
جزاكِ الله خيراا على المجهود
بس ليه مش كملتيه ؟؟

**اميرة بدينها2** · 11-07-2012, 10:35 PM

رد: مراجعة فارماكولوجى للخريجين

السلام عليكم ورحمة الله وبركاته

معلش كانت ظروف عندى وقلت ملفات بور بوينت هتبقى افضل علشان ال عايز يحتفظ بيها وتبقى مرجع موجود معاكم علطول

**اميرة بدينها2** · 11-07-2012, 10:38 PM

رد: مراجعة فارماكولوجى للخريجين

http://www.mediafire.com/view/?52lu5b59l34m72l

http://www.mediafire.com/view/?1p2e4gmwvoh2ld8

نهاية مقدمة علم الفارماكولوجى

**اميرة بدينها2** · 11-07-2012, 10:55 PM

رد: مراجعة فارماكولوجى للخريجين

Lipid solubility and drugs
1. more of the weak acid drug will be in the lipid-soluble form at alkaline pH.
2. more of the weak acid drug will be in the lipid soluble form at acid pH.
3. more of the weak base drug will be in the lipid soluble form at alkaline pH
4. A & C
5. B & C
Cytochrome-P450 INDEPENDENT oxidation
1. amine oxidase
2. epoxidation
3. N-oxidation
4. S-oxidation
5. deamination
A weak acid at acid pH:
likely to be lipid-soluble
probably will be uncharged
both
neither

Factor(s) which may change intrinsic drug clearance:

smoking
dietary considerations
age
genetic factors
all the above

Examples of biological second messengers:
1. cAMP
2. calcium
3. phosphoinositide
4. cGMP
5. all the above
Valium (diazepam) acts through this receptor system:
1. aspartate
2. GABA
3. acetylcholine
4. glutamate
5. serotonin

دى شوية أسئلة ياريت تجاوبوا عليها وإن شاء الله هضع الاجابات الصحيحة قريبا

إعـــــــلان

مراجعة فارماكولوجى للخريجين

تعليق

تعليق

تعليق

تعليق

تعليق

تعليق

تعليق

تعليق

تعليق